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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCLK1
All Species:
31.21
Human Site:
Y493
Identified Species:
62.42
UniProt:
O15075
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15075
NP_004725.1
740
82224
Y493
R
D
A
S
G
M
L
Y
N
L
A
S
A
I
K
Chimpanzee
Pan troglodytes
XP_522657
872
96662
Y636
R
D
A
S
G
M
L
Y
N
L
A
S
A
I
K
Rhesus Macaque
Macaca mulatta
XP_001082020
783
85228
Y514
R
D
G
S
A
M
V
Y
N
L
A
N
A
L
R
Dog
Lupus familis
XP_849124
740
82175
Y493
R
D
A
S
G
M
L
Y
N
L
A
S
A
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLM8
756
84135
Y509
R
D
A
S
G
M
L
Y
N
L
A
S
A
I
K
Rat
Rattus norvegicus
Q5MPA9
767
83998
Y512
R
D
G
S
A
M
V
Y
N
L
A
S
A
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511397
792
88039
Y554
R
D
A
S
G
M
L
Y
N
L
A
S
A
I
K
Chicken
Gallus gallus
XP_417099
1048
115422
Y799
R
D
A
S
G
M
L
Y
N
L
A
S
A
I
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q501V0
422
47914
T194
S
F
T
E
R
D
A
T
R
V
L
Q
M
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7PLI7
748
82953
K493
G
N
F
A
I
V
F
K
I
K
H
R
Q
T
G
Honey Bee
Apis mellifera
XP_394386
670
74883
R441
H
S
H
H
I
V
H
R
D
V
K
P
E
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189418
661
74296
N433
G
K
E
K
M
I
E
N
E
V
S
I
L
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.4
65.3
99.8
N.A.
96.4
65.3
N.A.
86.2
63.7
N.A.
24.7
N.A.
29.8
41
N.A.
52.3
Protein Similarity:
100
80.1
77.5
99.8
N.A.
97.3
77.8
N.A.
88
64.9
N.A.
35
N.A.
47.5
57.9
N.A.
65.9
P-Site Identity:
100
100
60
100
N.A.
100
66.6
N.A.
100
100
N.A.
0
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
86.6
100
N.A.
100
86.6
N.A.
100
100
N.A.
13.3
N.A.
20
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
9
17
0
9
0
0
0
67
0
67
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
0
0
0
9
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
0
9
9
0
0
9
0
9
0
0
0
9
0
0
% E
% Phe:
0
9
9
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
17
0
50
0
0
0
0
0
0
0
0
0
9
% G
% His:
9
0
9
9
0
0
9
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
0
17
9
0
0
9
0
0
9
0
50
0
% I
% Lys:
0
9
0
9
0
0
0
9
0
9
9
0
0
0
50
% K
% Leu:
0
0
0
0
0
0
50
0
0
67
9
0
9
17
17
% L
% Met:
0
0
0
0
9
67
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
9
0
0
0
0
0
9
67
0
0
9
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
9
% Q
% Arg:
67
0
0
0
9
0
0
9
9
0
0
9
0
9
17
% R
% Ser:
9
9
0
67
0
0
0
0
0
0
9
59
0
0
0
% S
% Thr:
0
0
9
0
0
0
0
9
0
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
17
17
0
0
25
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _